Thursday, August 11, 2022
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 Fintech Zoom
  • Markets
    • Forex Market
    • Bonds & Rates
    • Stock Market Guides
      • Stock Market YTD Returns – Benchmark Returns
      • Forex Trading Beginners Guide to find out just how to trade Forex
      • Stocks
      • Can Fake News Impact The Stock Market?
      • How to Copy Trade On Covesting Module Successfully: Step By Step Guide
      • The Ultimate Guide to Penny Stocks 2021
      • What News affects the Stock Market
      • How to interpret Stock Market news?
      • What is reliable Stock Market news?
      • Stocks in Market: Consider Investing These 2 Stocks
      • Does news really affect the Stock Market?
      • Friday Stock Market News US
      • How to read stock market news?
      • How news affects the Stock Market?
      • How to buy stocks?
      • Bank of America: investors should buy
      • How to Invest Money
        • How To Save Money
        • How to Make Money Online
        • How to Track Expenses
        • How to Create a Budget
    • Stocks To Buy Now
    • Commodities
      • Industrial Metals
        • Live Price of Nickel per Ounce
        • Copper
      • Energy
        • WTI Oil Prices
        • Natural Gas – Live Prices
        • Brent Crude
        • Crude Oil
      • Agricultural Products
        • Corns
      • Livestock & Meat
        • Lean Hogs
      • Precious Metals
        • Silver
        • Live Spot Palladium Price per Ounce
        • Platinum
        • Gold
          • What Are the Advantages of a Gold 401k Rollover?
          • GoldCo Review – How to Protect Your IRA With Gold
          • Price of Gold
          • 5 Ways In order to Buy Gold
          • Gold Price Chart
          • Gold Futures
          • Best Place to Buy Gold
    • Breaking Stock Market News
    • Europe
      • DAX
      • Russel 2000 (RUT)
      • STOXX Europe 600 Index Overview (SXXP)
      • Euro Stoxx 50
      • CAC
      • FTSE 100
        • Lloyds Share Price. LLOY – Stock Quote, Charts, Trade History
    • Australia
      • S&P/ASX 200
        • Virgin Australia
        • EML Payments Limited (ASX: EML) Stock Price & News
    • Asia
      • Nikkei
      • HSI – Hang Seng Index Overview
      • NSE
        • Tata Motors Limited Share Price Today, Stock Price, Live NSE
    • United States
      • Nasdaq
        • Apple
        • Okta, Inc. (OKTA) Stock Price, News & Quote
        • Upstart Holdings, Inc. (UPST) Stock Price, News & Quote
        • Comcast
        • NVCN Stock
        • Facebook Stock – FB Stock
        • Sundial Growers Inc. (SNDL) Stock Price & News
        • United Airlines
        • ContextLogic Inc. (WISH) Stock Price, News & Quote
        • SoFi Technologies, Inc. (SOFI) Stock Price & News
        • Lucid Group, Inc. (LCID) Stock Price, News & Quote
        • Airbnb, Inc. (ABNB) Stock Price, News & Quote
        • Ocugen, Inc. (OCGN) Stock Price, News & Quote
        • CLOV Clover Health Investments Corp. (CLOV) Stock Price, News & Quote
        • Adobe
        • Castor Maritime Inc. (CTRM) Stock Price, News & Quote
        • Onconova Therapeutics, Inc. (ONTX) Stock Price & News
        • Sanofi
        • AbbVie
        • ASML
        • NVAX Stock Price, News, Quote & History | Novavax, Inc. (NASDAQ: NVAX)
        • Workhorse Stock – Workhorse Group Inc. (NASDAQ: WKHS)
        • Dollar Tree
        • Tractor Supply
        • BKNG Stock
        • DKNG Stock
        • BKNG Stock
        • Amazon Pay
        • American Airlines
        • Moderna Stock
        • AMD Stock
        • AstraZeneca
        • Broadcom
          • Broadcom
        • ElectraMeccanica
        • Kandi
        • Facebook
        • Tesla Stock
          • Tesla Stock Price
          • Dow Jones
            • Mega-Cap Stocks
            • Facebook Libra
            • Frontier Airlines
            • Bristol-Myers Squibb
            • BABA
            • TJX
            • Marijuana Stocks – An Industry Overview
            • Bank of America – Best: America’s Best Banks
            • Walgreens
            • Goog
        • Gilead
        • Li Auto
        • Lockheed Martin
        • Microsoft
        • Netflix
          • Netflix Not Working? 8 Ways to Fix Netflix Issues
          • Netflix Stock
        • Nikola
        • Paypal
          • PayPal Stock Price
        • Pinduoduo
        • Roku Stock
        • T-Mobile
        • Ticketmaster
        • Nvidia
        • Costco Stock
          • Costco
        • Pepsi
        • Amazon
        • Petco
        • BioNTech
        • Zoom Stock
        • Gevo, Inc. (GEVO) Stock Price, News, Quote & History
        • MAXN: Maxeon Solar Technologies Ltd Stock Price & News
        • Gamida Cell Ltd. (GMDA) Stock Price, News & Quote
        • MyMD Pharmaceuticals Inc – Stock Price, Quote and News
        • Electrameccanica Vehicles Corp. (SOLO) Stock Price & News
        • Ideanomics, Inc. (IDEX) Stock Price, News & History
        • Nano Dimension Ltd. (NNDM) Stock Price & News
        • Vinco Ventures, Inc. (BBIG) Stock Price, News & Quote
        • Amesite Inc. (AMST) Stock Price, News & Quote
        • Cenntro Electric Group Limited (NAKD) Stock Price
      • Dow Jones
        • UnitedHealth Group
        • Verizon
        • Visa
        • Walgreens
        • Walmart
        • 3M
        • Amgen
        • Apple Stock
        • Boeing Stock
        • Caterpillar
        • Chevron
        • Cisco
        • Dow Inc.
        • Goldman Sachs
        • Honeywell
        • IBM
        • Intel
        • Johnson & Johnson
        • McDonald’s
        • Merck
        • Microsoft
        • Nike
        • Procter & Gamble
        • Salesforce
        • Coca-Cola
        • The Home Depot
        • The Travelers Companies
        • Disney
          • Disney Stock Price
      • NYSE Arca
      • NYSE American (AMEX)
        • Zomedica Corp. (ZOM) Stock Price, News & History
        • Ra Medical Systems, Inc. (RMED) Stock Price & News
      • OTC Markets
        • TSNP Stock
        • CYDY Stock
        • OZSC Stock – Ozop Energy Solutions Inc. (OZSC: OTC)
        • Bergio International, Inc. (BRGO) Stock Price & News
        • American Leisure Holdings, Inc. (AMLH) Stock Price & News
        • Healthier Choices Management Corp HCMC:OTCPK
        • ICA Stock
        • AABB Stock – Asia Broadband Inc (AABB:OTC)
      • NYSE Arca
        • Senseonics Holdings, Inc. (SENS) Stock Price & News
        • BNKU Stock – MicroSectors US Big Banks Index 3X Leveraged
      • S&P 500
      • NYSE
        • CHPT Stock (NYSE: CHPT)
        • Wells Fargo & Company (WFC) Stock Price, News, Quote
        • Ford Motor Company (F) Stock Price, News & Quote
        • Ford Motor Company (NYSE: F) Stock Price, News & Quote
        • DigitalOcean Holdings, Inc. (DOCN) Stock Price, News & Quote
        • Wells Fargo & Company (WFC) Stock Price, News, Quote
        • Twitter, Inc. (TWTR) Stock Price, News & Quote
        • QuantumScape Corporation (QS) Stock Price, News & Quote
        • Skillz Inc. (SKLZ) Stock Price, News & Quote
        • SOS Limited (NYSE: SOS) Stock Price, News & History
        • FuboTV Inc. (FUBO) Stock Price, News & History
        • Uber Stock
        • BABA Stock – Alibaba Group Holding Ltd. (NYSE: BABA)
        • Accenture
        • Jumia Stock
        • IPOF Stock – Social Capital Hedosophia Holdings Corp. VI
        • Amwell Stock
        • CCIV Stock – Churchill Capital Corp. VII (CVII)
        • Nokia Corporation (NOK) Stock Price, News, Quote & History
        • GME Stock
          • GME Short Interest: GameStop Short Interest Ratio
        • Palantir Stock
        • Snowflake Stock
        • Boeing
        • AMC Stock
        • Disney Stock
        • Vaxart Stock
        • NIO Stock
        • Kodak Stock
        • KODK: Eastman Kodak Company
        • AT&T
        • Square Stock
        • PFIZER
        • Bank of America
          • Bank of America Stock
        • Berkshire Hathaway
        • Danaher
        • General Motors
        • Oracle (ORCL) Stock Price, News & Quote
        • Mastercard
          • Mastercard News
        • Novartis AG
        • Royal Caribbean
        • Lowe’s
        • Southwest Airlines
        • Target
        • Taiwan Semiconductor
        • Unilever
        • NGA Stock
        • Abbott
        • SPY Stock
        • Toyota
        • Thermo Fisher Scientific
        • Raytheon Technologies
        • Total
        • Citigroup
        • XPeng
      • GE Stock
      • Large-Cap by Market Cap Today
        • ExxonMobil
        • Amazon
        • CVS Pharmacy
        • China Mobile
        • PNC
        • Qualcomm
        • Philip Morris
      • Stock Market
        • Calculator CleanMate
          • Calculator Car Service
            • Stripe News
            • American Airlines reduce flights to $40
            • Stock Market: U.S. Stocks Turn Higher
            • EOS
        • Stock Market Today March 30, 2020
      • Stock Futures
        • Bank of America Stock Falls 3%
        • Walmart Hours
        • Uber Eats
        • U.S. Stock Market Opens Lower
        • Pound to Euro
      • Top Companies
        • Amazon Prime
        • Facebook
        • Zoom
        • Twitter
        • Zillow
        • eBay
    • Stock Market “Best of…”
      • How to Get News Before Stock Market Opens
      • Best Stock Trading Apps of 2020
      • Best Fintech Stocks 2020
      • Best Brokers for ETFs Investing
      • Best dividend stocks
      • Best Online Brokers for Beginners 2020
      • Trading Platform Review – Prime XBT
      • Best Forex Brokers 2020
      • 7 Best Global Forex Brokers for 2022
      • Best Online Brokers for Stock Trading 2020
  • Cryptocurrencies
    • Crypto Reviews
      • MyCointainer review – what you need to start earning passive income on a staking platform
    • How can I find legit crypto casinos?
    • Crypto “Best Of…”
      • Best 5 Crypto Casinos in Canada
      • Best Crypto Wallets 2020
      • Bitcoin Debit Card for USA
      • Best Cryptocurrency to Invest in 2021
      • Best Crypto Hardware Wallets of 2020
      • Best Cryptocurrency Exchange 2021
      • Best Crypto to Invest in
      • Greatest Cryptocurrency Tax Software program 2020
      • Greatest ICO itemizing websites ICO Score Businesses (2019) | Cryptocurrency ICO Checklist | ICO Calendar
      • Best Crypto Trading Bot
      • Best Cryptocurrency Exchanges | April 2020
    • Cryptocurrency News
      • Cryptocurrency Analysis
      • What Happens to Your Cryptocurrency If You Die?
      • Crypto Exchange News
      • Exchange Fee
      • Bitcoin News
        • Current Bitcoin News
          • Bitcoin Price Analysis is now value as a lot as PayPal
          • Bitcoin Price Volume Decline with Lowering Volatility
      • Ethereum News
      • Blockchain News
      • Ripple News
      • ICO News
      • Crypto Exchange Ranking
    • Top Cryptocurrencies
      • Bitcoin
      • Ethereum (ETH)
      • USD Coin Price Today
      • Stellar
      • Bitcoin
        • Bitcoin Calculator
          • BTC to USD Converter
          • Bitcoin Preev
        • Buy Bitcoin
          • Buy Bitcoin With Gift Card
          • Buy Bitcoin with Credit Card
          • Buy Bitcoin Cash
          • Buy Bitcoin Anonymously
          • Buy Bitcoin with credit card
          • Buy Bitcoin with Prepaid Card
          • Buy Bitcoin with Paypal
          • Buy Bitcoin Near Me
          • Buy and Sell Bitcoin
          • Buy Bitcoin: Best Ways to Buy BTC Instantly
          • Buy Bitcoin at Walmart
          • Buy Bitcoin ATM
          • Buy Bitcoin Through Paypal
          • Buy Bitcoin Without ID
        • Bitcoin Price
          • Bitcoin Price USD
          • Bitcoin Price History
          • Bitcoin Price Live
          • Bitcoin Price Live Ticker
          • BTC to USD
          • Price of Bitcoin
          • Price Charts – Bitcoin Price
          • Bitcoin 가격
          • Bitcoin Price Prediction
        • Bitcoin “Best of…”
          • 23 Best Place to Buy Bitcoin Online 2020
          • Bitcoin Betting
          • Best Bitcoin Sports Betting Sites 2020
        • How to Earn Bitcoins Without Mining
        • Burritos or Bitcoin – We need more promotions like this.
      • Cardano
      • Ethereum
        • Ethereum Price Today
        • Ethereum Worth
      • Ripple
        • Ripple Price
        • Ripple
      • Tether
      • Bitcoin Cash
      • Dogecoin
        • Dogecoin News
        • Dogecoin News
      • Litecoin
        • Litcoin Price Today – LTC to USD Live Chart
    • Companies
      • Coinbase – How to Buy Bitcoin?
        • Best Site to Buy Bitcoin
      • Binance Coin
      • COINBASE
      • Binance News
    • Bitcoin Guides
      • Bitcoin
        • Bitcoin for Beginners
        • Who Owns Bitcoin ?
        • Bitcoin Tax
        • How to Make Money with Bitcoin
        • Bitcoin Hoje
        • How Many Bitcoin are There 2021?
        • Mercado Bitcoin
      • How to Invest in Bitcoin?
      • Bitcoin Price Guide
        • How Much is 1 Bitcoin Worth?
        • Bitcoin Value
        • Bitcoin Price Prediction
        • Bitcoin BTC Price
      • How to Mine Bitcoin on PC
        • How To Mine Cryptocurrency? A Definitive Guide
        • How Long does it Take to Mine 1 Bitcoin?
      • How To Invest In Cryptocurrency?
      • Bitcoin Halving
        • Bitcoin Halving
      • How to Buy Bitcoin
        • Best Site to Buy Bitcoin
        • Bitcoin ATM near me
        • Easiest Way to Buy Bitcoin
        • What can you Buy with Bitcoin?
        • Where to buy Bitcoin?
        • How to get a lot of bitcoin for free?
      • Wallets
        • Offline Wallets for Bitcoin
        • Bitcoin Wallet
  • Luxury
    • Food & Drink
      • Most Expensive Steak
        • The Ultimate Guide to Wagyu Steak, the World’s Many Elegant Steak
      • Most Expensive Bourbon
        • 10 Greatest Bourbon Whiskey of the World
    • Style
      • Luxury Brands
        • Luxury Designer Sports Equipment Worth Collecting
        • Best Luxury Clothing Brands
      • Luxury Real Estate
        • 10 of the World’s Most Expensive Homes
        • 4 Things You Need to Know About Luxury Apartments
      • Luxury Watches
        • Hublot – Swiss Luxury Watches & Chronographs
        • Rolex – Swiss Luxury Watches
        • Most Expensive Watches
    • Motors
      • Luxury Aviation
      • Luxury SUV
        • Best Luxury SUVs for 2020
      • Luxury Cars
        • The grey and black Ford Mustang from Gone in 60 Seconds remake, is up for sale.
        • Mercedes-Maybach S680 Limited Edition
        • SSC Tuatara Hypercar Flying at 282.9 mph
        • Porsche
        • Chevrolet Corvette C8 Specs – Ultimate Guide
        • Guide to the Tesla Cybertruck
        • Best Luxury Cars
        • The 20 Most Fastest Production Cars 2021
        • Best Luxury Sports Car
        • The Best Luxury Sports Cars
      • Luxury Yachts
        • Supercar of the Sea – Tecnomar for Lamborghini 63 Yacht
        • The 10 Largest Super Yachts in the World
        • 10 Most Expensive Luxury Yatchs
    • Travel
      • Luxury Hotel
        • COMO Hotels and Resorts
        • Hilton – Conrad Hotels and Resorts
        • Ritz Carlton Hotels
        • The Best Luxury Hotels in the World
        • Marriott
      • 14 Best Luxury Travel Destinations
      • Luxury SPA
        • The Best Spas & Wellness Centers in Miami Beach
        • Best Luxury Yoga Retreats
    • Tech
  • Reviews
    • Travel – Reviews
      • The Best Carry-On Luggage for Every Trip and Budget
      • The 7 Best Tents for your comfort or your family.
      • The 15 Best Beach Chairs?
    • Home & Garden
      • 10 Of The Best Washers And Dryers To Make your Life Easier
      • The 10 Best Portable Air Conditioners
      • Beverage cooler vs mini fridge
      • Can I use bose cube speakers with any receiver
      • The 7 Best Dehumidifier and Air Purifier Combo
      • The Greatest Robot Vacuums to Assure Cleaner Floors
      • The 11 Best Air Purifiers in 2021
      • The 6 Best Cordless Stick Vacuum in 2021
    • Health & Fitness
      • The 8 Best Car Bike Racks
      • The Best Mosquito Repellents & Bug Sprays
      • The 10 Best Electric Toothbrushes, According to Dentists
      • 15 Best Water Bottles of 2021
      • 15 Best Water Shoes For Adventurous Men
      • 10 Best Yoga Mats of 2021— For Every Yoga Lover
    • Office
      • The 12 Best Standing Desk of 2021 for Office.
      • The 10 Best Office Chairs in 2021
      • The 13 Best Laser Prints for great print quality at a low cost
      • Best Laptop Backpacks to Fashionable Professionals
    • Tech Reviews
      • The 11 Best Karaoke Microphone in 2021
      • Mobile Reviews
        • Vivo Y20T Mobile – Price and Specifications
      • The 9 Ideal Waterproof Phone Cases of 2022
      • Tesla Phone: Details & Prices for the Futuristic New Mobile…Apple are you ready?
      • GoPro Vs Contour: Which One Is Better in 2021?
      • Best wireless car charger
      • Best drones under 300
      • The 9 Best Laptop Under 500USD
      • The 18 Best Noise-Cancelling Headphones of 2021
      • Top 10 Best Smartwatches in 2021 – The Ultimate Buying Guide & Reviews!
      • Best underwater drone
      • Best dash cam for 2021
    • Style
      • The 14 Best Electric Shavers
      • The 13 Best Hair Clippers For Men – For Barbers and Hairstylists
  • Lifestyle
    • Weather Tomorrow
    • Travel
      • How Late Is The Closest Grocery Store Open
      • Universal Pass – How to Get Universal Pass?
      • December Global Holidays on the World
      • Leisure Travel Vans
    • Life
      • College Dorm Party – Are you Looking for the Perfect Party?
      • College Dorm Party – Are you Looking for the Perfect Party?
      • Are you looking for good morning messages for her? Here’s the right place. 101 Messages.
      • Good Tinder Bio Ideas That Will Aid You Obtain Much More Matches
    • Near Me
      • Staples Near Me – Store Locator
      • Walmart Near Me – Store Locator
      • Restaurants Near Me
      • Home Depot Near Me – Store Locator
    • Health
      • Ulta Near Me – Ulta Locations
      • Bottled and Jarred Packaged Goods – Simple Guide
      • Difficult Person Test – Am I a Difficult Person?
      • Sex
      • Covid-19
        • Direct Payments in coronavirus
    • Tech
      • Unlock
        • Is your Snapchat account locked? Here’s how to unlock it
      • Download
        • Y2mate Com 2022 download MP3 and MP4 videos from Youtube
      • Settings
        • Picuki – The Ultimate Guide for Picuki Instagram Story Viewer
        • Smihub – The ultimate Guide to Anonymous Instagram Story Viewer
        • APK File – Complete Guide to work with APK Files
        • Just how to go down a pin in Google Maps
        • xResolver: Find Alternatives Sites Very similar to xResolver.com
        • IG Tools and Alternatives websites to igtools. net
        • Different methods to check your Spotify stats
        • https www Twitch Activate Code – How to Activate Twitch TV
        • Exactly How To Allow Dark Mode In Snapchat
      • Error
        • How do I fix Hulu Error Code P-DEV320?
        • [pii_email_cb926d7a93773fcbba16] – How to Fix this Problem on Microsoft Outlook?
        • What is error 0x0 0x0? How to fix it? Special Guide
      • Login
        • Xfinity Login – Ways to Sign In to My Account
        • 192.168.0.1 – Router Login Admin
        • Z Library – The complete overview to virtual library
        • 192.168.1.1 – Router IP Admin Panel
        • HBOmax/tvsignin: How to Sign in to HBO Max?
        • Tips About How to Allow DApp Browser on Trust Wallet (2022)
        • Disneyplus com Login Begin: Disney+ Activation with 8 Digit Code
        • How to Sign in to Prime Video on your TV? Amazon.com mytv login
        • Everything about Dissociation of Yahoo Mail from AT&T Communication Service
        • Facebook Not Working? Common Facebook Issues and to fix them
        • Facebook Account Hacked – How to Recover?
        • 1and1 webmail 2021: the ultimate guide to login ionos webmail
        • TWC Roadrunner Email Login
        • Email That Doesn’t Require Phone Number – Find Here 15 Email Providers
        • Zoom.com Login
        • Verizon Email Login – How to login in to Verizon .net?
        • Bellsouth.net Email Login
        • Login to CompuServe Email Account – 2 Ways to Login
        • How to share your screen on Discord for PC and Smart Phone.
        • ATT Email Login – How to Log in Into AT&T By Yahoo
        • Telstra Bigpond Webmail Login – Your Simple Guide
        • AOL Login – How to do a Quick Login to an AOL Email Account?
        • GoDaddy Email Login – How to Login to my GoDaddy Account? 3 Ways
        • Yahoo Chat Room – Is It Still Available?
      • Is It Down?
        • Is Netflix Down?
        • Is Snapchat down now?
        • INSTAGRAM DOWN 2022: HOW TO SOLUTION YOUR APP IN YEAR’S FIRST MAJOR FAILURE
      • iPhone 12
    • Famous People
      • Do you Know the Legacy of Stamen Grigorov?
      • Markie Post Bio – What is She Doing Now?
      • Robert Sheehan: 15 facts you didn’t know about
    • Weather Tomorrow
    • Real Estate
      • Aston Martin Residences
      • The Best Miami Luxury Homes
    • Cars
      • Find Car Detailing Near Me
      • The Best Supercars
      • Best Electric Cars
      • Best Time to Buy a Car
      • Find the Best Cars for Sale
    • Entertainment
      • Clubs
        • Sqm Club – Find here Why it’s so Popular These Days.
      • Streaming
        • What is www IFVOD TV ? The Complete Guide.
        • VIPLeague Review – The Complete Guide & VIPLeague Alternative
        • VIPRow Sports – The Complete Guide & Best VIPRow Alternative
        • USTVGO.TV – 80+ Live Stream TV Channels 
        • What is www IFVOD TV ? The Complete Guide.
        • VIPLeague Review – The Complete Guide & VIPLeague Alternative
        • VIPRow Sports – The Complete Guide & Best VIPRow Alternative
        • USTVGO.TV – 80+ Live Stream TV Channels 
        • Streameast & Alternatives Websites and Competitors
        • Best Free Movie and TV Streaming Services that will saving your Money
        • VIPBox & 10 Web Sites Like VIPBox for Live Sports Streaming
        • 6streams – Alternatives Websites To See Boxing, MMA and NFL
      • Emojis
        • Emoji People
      • Music
        • Spotify
      • Movies
        • Project Free TV: 40 Best Alternatives to See Movies in 2021
        • Horror Movies: The 15 Best Horror Movies of this Century
        • SD Movies Point 2022: Download HD New Bollywood Movies
        • 123mkv Movies 2022 – Download Movies: Is It Legal & Safe To Use In India?
        • ibomma.com Movie – iBOMMA Telugu Movies New 2022 Free Download
        • HDhub4u Movie Download 2022 – Latest Bollywood Hollywood HD Movies
        • Vegamovies HD Movies – How to Download Movies From Vegamovies nl, Vegamovies cc?
        • HuraWatch: Are you searching for Watch Free Online Movies?
        • Horror Movies: The 15 Best Horror Movies of this Century
        • TamilYogi HD Movies – Download the Latest Hindi & Tamil Movies
        • Filmyzilla 2022 – Is it Legal use Filmyzilla Bollywood Movies Download?
        • TinyZone 2022: Free Streaming Web Site To See Online Videos and Reveals
        • 9xmovies app – How can you Download Bollywood Movies?
        • GenYouTube Downloader GenYT Download YouTube Videos Online Totally Free Legal Or Not?
        • HDhub4u Movie Download 2022 – Latest Bollywood Hollywood HD Movies
        • Bolly4u Download Bollywood Hollywood Hindi Referred To As Movies Totally Free
        • Vegamovies HD Movies – How to Download Movies From Vegamovies nl, Vegamovies cc?
        • Movierulz 2022 Most Current HD Movies Download on Movierulz.com
        • TamilYogi HD Movies – Download the Latest Hindi & Tamil Movies
        • Moviezwap Bollywood, Tamil, Hollywood, Telugu Movies HD Download And Install 2022 MoviezWap.org
        • TinyZone 2022: Free Streaming Web Site To See Online Videos and Reveals
        • GenYouTube Downloader GenYT Download YouTube Videos Online Totally Free Legal Or Not?
        • Bolly4u Download Bollywood Hollywood Hindi Referred To As Movies Totally Free
        • Movierulz 2022 Most Current HD Movies Download on Movierulz.com
        • Moviezwap Bollywood, Tamil, Hollywood, Telugu Movies HD Download And Install 2022 MoviezWap.org
        • Moviesflix 2022: All Hindi Bollywood, Hollywood 300Mb 480p, 720p, 1080p Internet Series and TV Download
        • ThePirateBay3 – Best 7 Similar Alternative Torrent Websites
        • Save From Net – Free Online Video Downloader By Savefrom.net
        • Queenslandmax Review – Is Queenslandmax a Fraud or legitimate?
        • Jio Rockers 2022 Telugu Movies – Download Now
        • Watch Free Movies Online Without Registration – Best Streaming Sites 2022
        • Einthusan Alternatives: Sites For Streaming Free Movies & TV Reveals
        • Downloadhub – Best Bollywood Movies Websites
        • MoviesFlix 2021 – Watch Free HD Movies
        • Afdah Movies – Watch Free HD Movies 2021
        • FZtvseries 2021: Watch Latest Movies
        • Losmovies 2021: Best Cost-free English Movies Website
        • Cmovies 2021: Watch Free HD Movies Online & Best Alternatives
        • Stream2Watch – The Guide to the 10 Best Alternatives
        • Project Free TV: 40 Best Alternatives to See Movies in 2021
        • Websites Like SolarMovie (SolarMovie Alternatives): Top Picks
        • 14 Working CouchTuner Alternatives in 2021
        • PirateBay Proxy List – Is your Pirate Bay Blocked?
        • Aashram Season 3: Everything You Need To Know
      • Gambling
        • How the UK Set the Standards for Online Gaming
        • A Look into Live Casino Technology
        • 9 Things You Should Know Before Gambling with Crypto
        • 3 Methods of Online Gambling That Have Become Popular in the Past Year
        • Which Casinos Are The Most Financially Successful in the History of Vegas?
        • Why would I want to play free slots?
        • Wild symbols in slot machines explained
        • How to avoid cheating and fraud in online casinos
        • Live Casinos Online: A Better Experience for Seasoned Players?
        • Main perks and benefits of being loyal to one gambling platform
        • Best Sports Betting Strategies
        • A Closer Look at Online Crypto Casinos
        • How do Sports Betting Odds Work? – The Ultimate Guide.
        • Understanding Different Types Of Online Slots
        • How to Read Odds: NBA Odds
        • Online Casinos
        • Betting
          • US Betting Sites
          • UK Betting Sites
          • Asia Betting Sites
          • The Best Sports Betting Sites
          • NBA Betting Sites
          • NFL Betting Sites In 2021
      • Animation
        • AnimeUltima – The Best 13 Alternatives to Watch Anime Online
        • Webtoon XYZ – The Complete Guide about XYZ Webtoon
        • Everything You Need To Find Out About AniMixPlay
        • KissCartoon 2021- Best 8 Alternatives to See Cartoon Online Free
        • Watch Anime Free – 21 Free Anime Sites to Watch Online the Best Anime
        • Mangastream is Gone… But there are 15 MangaStream Alternatives!
        • Bleach backs with a new manga´s chapter: see date & details
        • Baki Season 4 release date & all info – New Trailer
      • Gaming
        • Keyboards
          • Best 60 Percent Keyboard 2021
        • The very best Free PC Games to enjoy in 2021
        • Zombie Games – Do you know What are the Best Games for PC in 2021?
        • Rimworld
          • The best Rimworld mods
        • Final Fantasy
          • FFXIV Classes Guide on Final Fantasy 14 – select the best job.
        • What’s the Best MMORPG for PC ?
        • Cities – Skylines Mods
        • MBC2030 live login and Steps to mbc2030.live registration
        • Just How to Register WPC2023 Account? Everything Concerning WPC 2023
        • Wpit18 Com Login and Registration Guide
        • Sw418 Login: Complete Guide to Login and Registration procedure
        • Pacman 30th Anniversary: All About The Traditional Game’s Background
        • WPC2021 Live Dashboard – Complete Details Of WPC2021 Live Dashboard Login
        • WPC2025 Live Login, Why People Love To Play This Game?
        • WPC2026 Live – The Ultimate Guide for WPC2026.live Login
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Amgen – BeiGene Broadcasts the Approval in China of BLINCYTO® (Blinatumomab) for Injection for Grownup Sufferers with Relapsed or Refractory B-Cell Precursor Acute Lymphoblastic Leukemia (ALL)

Judie Simms by Judie Simms
December 8, 2020
in Amgen
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Home » Amgen – BeiGene Broadcasts the Approval in China of BLINCYTO® (Blinatumomab) for Injection for Grownup Sufferers with Relapsed or Refractory B-Cell Precursor Acute Lymphoblastic Leukemia (ALL)

Amgen – BeiGene Broadcasts the Approval in China of BLINCYTO® (Blinatumomab) for Injection for Grownup Sufferers with Relapsed or Refractory B-Cell Precursor Acute Lymphoblastic Leukemia (ALL)

BEIJING & CAMBRIDGE, Mass.–(BUSINESS WIRE)–BeiGene, Ltd. (NASDAQ: BGNE; HKEX: 06160), a commercial-stage biotechnology firm centered on growing and commercializing progressive medicines worldwide, in the present day introduced that the China Nationwide Medical Merchandise Administration (NMPA) has accepted BLINCYTO® (blinatumomab) for injection for the remedy of grownup sufferers with relapsed or refractory (R/R) B-cell precursor acute lymphoblastic leukemia (ALL). The biologics license utility (BLA) had been submitted by Amgen and acquired precedence overview by the Middle for Drug Analysis (CDE) of the NMPA. Developed by Amgen and licensed to BeiGene in China below a strategic collaboration commenced earlier this yr, that is the primary approval for BLINCYTO in China and BeiGene’s first product licensed from Amgen to be newly accepted. With this approval, BLINCYTO has turn into the primary bispecific immunotherapy accepted in China.

“This approval of BLINCYTO provides us with an opportunity to offer adult patients in China with relapsed or refractory B-cell precursor ALL the first approved immunotherapy treatment for their disease. BLINCYTO is the first immunotherapy to demonstrate superior overall survival versus chemotherapy, more than doubling patients’ chances for survival, when used in first salvage R/R ALL in studies outside of China,” commented Xiaobin Wu, Ph.D., General Supervisor of China and President of BeiGene. “We are working to ensure BLINCYTO is available to patients in China as soon as possible. Our commercial organization of more than 1,500 people in China is excited to add BLINCYTO to our product portfolio, which now includes six approved cancer treatments.”

The approval of BLINCYTO was primarily based on outcomes from the Section Three trial (NCT03476239) in China evaluating the efficacy and security of BLINCYTO in grownup sufferers with Philadelphia-negative R/R B-cell precursor ALL. Outcomes of the interim evaluation of 67 sufferers confirmed that the efficacy leads to Chinese language topics have been usually in keeping with these within the world and Japan research in topics with Philadelphia-negative R/R ALL. The entire response/full response with partial restoration of blood cells (CR/CRh) fee inside two cycles of BLINCYTO remedy (the first endpoint) was 47.8% (32 of 67 topics; 95% CI: 35.4, 60.3). The median general survival time was 9.6 months (95% CI: 6.4, not estimable). The protection profile noticed for Chinese language topics on this examine was in keeping with that noticed within the world research evaluating BLINCYTO in R/R ALL. No new security dangers have been recognized primarily based on these interim analyses of adversarial occasions in Chinese language topics.

“Our collaboration with BeiGene is advancing Amgen’s oncology pipeline for patients with significant unmet medical needs. We are confident the approval of BLINCYTO in China has the potential to make a meaningful difference to adult patients with R/R B-cell precursor acute lymphoblastic leukemia,” mentioned My Linh Kha, Vice President & General Supervisor, Amgen Japan Asia-Pacific (JAPAC). “We are deeply committed to continuing to bring therapeutic options to treat debilitating cancers for patients in China, while also actively supporting the Government’s focus on healthy aging through innovative products and initiatives designed to prevent chronic diseases, such as cardiovascular disease and fragility fracture.”

About Acute Lymphoblastic Leukemia (ALL)

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Acute lymphoblastic leukemia (ALL), also referred to as acute lymphocytic leukemia, is a quickly progressing most cancers of the blood and bone marrow that happens in each adults and youngsters1. ALL accounts for about 20% of all grownup leukemia, and in China there have been an estimated 82,607 new circumstances of leukemia in 20182,3. In youngsters, the relapse fee of ALL is sort of 10%, whereas in adults the relapse fee is nearer to 50%4.

About BLINCYTO® (blinatumomab)

BLINCYTO is a bispecific CD19-directed CD3 T cell engager (BiTE®) immuno-oncology molecule that binds particularly to CD19 expressed on the floor of cells of B-lineage origin and CD3 expressed on the floor of T cells.

BiTE molecules are a sort of immuno-oncology remedy being investigated for combating most cancers by serving to the physique’s immune system to detect and goal malignant cells. The modified molecules are designed to interact two completely different targets concurrently, thereby juxtaposing T cells (a sort of white blood cell able to killing different cells perceived as threats) to most cancers cells. BiTE immuno-oncology molecules assist place the T cells inside attain of the focused cell, with the intent of permitting T cells to inject toxins and set off the most cancers cell to die (apoptosis). BiTE immuno-oncology therapies are presently being investigated for his or her potential to deal with all kinds of cancers.

BLINCYTO was granted breakthrough remedy and precedence overview designations by the U.S. Meals and Drug Administration and is accepted within the U.S. for the remedy of:

  • relapsed or refractory B-cell precursor ALL in adults and youngsters.
  • B-cell precursor ALL in first or second full remission with minimal residual illness (MRD) larger than or equal to 0.1% in adults and youngsters. This indication is accepted below accelerated approval primarily based on MRD response fee and hematological relapse-free survival. Continued approval for this indication may be contingent upon verification and outline of scientific profit within the confirmatory trials.

Within the European Union (EU), BLINCYTO is indicated as monotherapy for the remedy of:

  • adults with Philadelphia chromosome detrimental CD19-positive relapsed or refractory B-precursor acute lymphoblastic leukemia (ALL).
  • adults with Philadelphia chromosome detrimental CD19-positive B-precursor ALL in first or second full remission with minimal residual illness (MRD) larger than or equal to 0.1%.
  • paediatric sufferers age 1 yr or older with Philadelphia chromosome-negative CD19-positive B-precursor ALL which is refractory or in relapse after receiving not less than two prior therapies or in relapse after receiving prior allogeneic hematopoietic stem cell transplantation.

In China, BLINCYTO is indicated for the remedy of grownup sufferers with relapsed or refractory B-cell precursor ALL.

Necessary U.S. Security Data

WARNING: CYTOKINE RELEASE SYNDROME and NEUROLOGICAL TOXICITIES

  • Cytokine Launch Syndrome (CRS), which may be life-threatening or deadly, occurred in sufferers receiving BLINCYTO®. Interrupt or discontinue BLINCYTO® and deal with with corticosteroids as really useful.
  • Neurological toxicities, which may be extreme, life-threatening or deadly, occurred in sufferers receiving BLINCYTO®. Interrupt or discontinue BLINCYTO® as really useful.

Contraindications

BLINCYTO® is contraindicated in sufferers with a identified hypersensitivity to blinatumomab or to any part of the product formulation.

Warnings and Precautions

  • Cytokine Launch Syndrome (CRS): CRS, which may be life-threatening or deadly, occurred in 15% of sufferers with R/R ALL and in 7% of sufferers with MRD-positive ALL. The median time to onset of CRS is 2 days after the beginning of infusion and the median time to decision of CRS was 5 days amongst circumstances that resolved. Carefully monitor and advise sufferers to contact their healthcare skilled for indicators and signs of great adversarial occasions comparable to fever, headache, nausea, asthenia, hypotension, elevated alanine aminotransferase (ALT), elevated aspartate aminotransferase (AST), elevated complete bilirubin (TBILI), and disseminated intravascular coagulation (DIC). The manifestations of CRS after remedy with BLINCYTO® overlap with these of infusion reactions, capillary leak syndrome, and hemophagocytic histiocytosis/macrophage activation syndrome. If extreme CRS happens, interrupt BLINCYTO® till CRS resolves. Discontinue BLINCYTO® completely if life-threatening CRS happens. Administer corticosteroids for extreme or life-threatening CRS.
  • Neurological Toxicities: Roughly 65% of sufferers receiving BLINCYTO® in scientific trials skilled neurological toxicities. The median time to the primary occasion was inside the first 2 weeks of BLINCYTO® remedy and the vast majority of occasions resolved. The most typical (≥ 10%) manifestations of neurological toxicity have been headache and tremor. Extreme, life‐threatening, or deadly neurological toxicities occurred in roughly 13% of sufferers, together with encephalopathy, convulsions, speech problems, disturbances in consciousness, confusion and disorientation, and coordination and stability problems. Manifestations of neurological toxicity included cranial nerve problems. Monitor sufferers for indicators or signs and interrupt or discontinue BLINCYTO® as outlined within the PI.
  • Infections: Roughly 25% of sufferers receiving BLINCYTO® in scientific trials skilled critical infections comparable to sepsis, pneumonia, bacteremia, opportunistic infections, and catheter-site infections, a few of which have been life-threatening or deadly. Administer prophylactic antibiotics and make use of surveillance testing as acceptable throughout remedy. Monitor sufferers for indicators or signs of an infection and deal with appropriately, together with interruption or discontinuation of BLINCYTO® as wanted.
  • Tumor Lysis Syndrome (TLS), which may be life-threatening or deadly, has been noticed. Preventive measures, together with pretreatment unhazardous cytoreduction and on-treatment hydration, ought to be used throughout BLINCYTO® remedy. Monitor sufferers for indicators and signs of TLS and interrupt or discontinue BLINCYTO® as wanted to handle these occasions.
  • Neutropenia and Febrile Neutropenia, together with life-threatening circumstances, have been noticed. Monitor acceptable laboratory parameters (together with, however not restricted to, white blood cell rely and absolute neutrophil rely) throughout BLINCYTO® infusion and interrupt BLINCYTO® if extended neutropenia happens.
  • Results on Potential to Drive and Use Machines: As a result of the potential of neurological occasions, together with seizures, sufferers receiving BLINCYTO® are in danger for lack of consciousness, and ought to be suggested in opposition to driving and fascinating in hazardous occupations or actions comparable to working heavy or doubtlessly harmful equipment whereas BLINCYTO® is being administered.
  • Elevated Liver Enzymes: Transient elevations in liver enzymes have been related to BLINCYTO® remedy with a median time to onset of three days. In sufferers receiving BLINCYTO®, though the vast majority of these occasions have been noticed within the setting of CRS, some circumstances of elevated liver enzymes have been noticed outdoors the setting of CRS, with a median time to onset of 19 days. Grade Three or larger elevations in liver enzymes occurred in roughly 7% of sufferers outdoors the setting of CRS and resulted in remedy discontinuation in lower than 1% of sufferers. Monitor ALT, AST, gamma-glutamyl transferase, and TBILI previous to the beginning of and through BLINCYTO® remedy. BLINCYTO® remedy ought to be interrupted if transaminases rise to > 5 occasions the higher restrict of regular (ULN) or if TBILI rises to > Three occasions ULN.
  • Pancreatitis: Deadly pancreatitis has been reported in sufferers receiving BLINCYTO® together with dexamethasone in scientific trials and the post-marketing setting. Consider sufferers who develop indicators and signs of pancreatitis and interrupt or discontinue BLINCYTO® and dexamethasone as wanted.
  • Leukoencephalopathy: Though the scientific significance is unknown, cranial magnetic resonance imaging (MRI) adjustments exhibiting leukoencephalopathy have been noticed in sufferers receiving BLINCYTO®, particularly in sufferers beforehand handled with cranial irradiation and antileukemic chemotherapy.
  • Preparation and administration errors have occurred with BLINCYTO® remedy. Comply with directions for preparation (together with admixing) and administration within the PI strictly to attenuate treatment errors (together with underdose and overdose).
  • Immunization: Vaccination with dwell virus vaccines just isn’t really useful for not less than 2 weeks previous to the beginning of BLINCYTO® remedy, throughout remedy, and till immune restoration following final cycle of BLINCYTO®.
  • Threat of Severe Adversarial Reactions in Pediatric Sufferers on account of Benzyl Alcohol Preservative: Severe and deadly adversarial reactions together with “gasping syndrome,” which is characterised by central nervous system melancholy, metabolic acidosis, and gasping respirations, can happen in neonates and infants handled with benzyl alcohol-preserved medication together with BLINCYTO® (with preservative). When prescribing BLINCYTO® (with preservative) for pediatric sufferers, contemplate the mixed every day metabolic load of benzyl alcohol from all sources together with BLINCYTO® (with preservative) and different medication containing benzyl alcohol. The minimal quantity of benzyl alcohol at which critical adversarial reactions may happen just isn’t identified. Because of the addition of bacteriostatic saline, 7-day luggage of BLINCYTO® answer for infusion with preservative include benzyl alcohol and are usually not really useful to be used in any sufferers weighing < 22 kg.

Adversarial Reactions

  • The most typical adversarial reactions (≥ 20%) in scientific trial expertise of sufferers with MRD-positive B-cell precursor ALL (BLAST Examine) handled with BLINCYTO® have been pyrexia (91%), infusion-related reactions (77%), headache (39%), infections (pathogen unspecified [39%]), tremor (31%), and chills (28%). Severe adversarial reactions have been reported in 61% of sufferers. The most typical critical adversarial reactions (≥ 2%) included pyrexia, tremor, encephalopathy, aphasia, lymphopenia, neutropenia, overdose, gadget associated an infection, seizure, and staphylococcal an infection.
  • The most typical adversarial reactions (≥ 20%) in scientific trial expertise of sufferers with Philadelphia chromosome-negative relapsed or refractory B-cell precursor ALL (TOWER Examine) handled with BLINCYTO® have been infections (bacterial and pathogen unspecified), pyrexia, headache, infusion-related reactions, anemia, febrile neutropenia, thrombocytopenia, and neutropenia. Severe adversarial reactions have been reported in 62% of sufferers. The most typical critical adversarial reactions (≥ 2%) included febrile neutropenia, pyrexia, sepsis, pneumonia, overdose, septic shock, CRS, bacterial sepsis, gadget associated an infection, and bacteremia.
  • Adversarial reactions that have been noticed extra incessantly (≥ 10%) within the pediatric inhabitants in comparison with the adults with relapsed or refractory B-cell precursor ALL have been pyrexia (80% vs. 61%), hypertension (26% vs. 8%), anemia (41% vs. 24%), infusion-related response (49% vs. 34%), thrombocytopenia (34% vs. 21%), leukopenia (24% vs. 11%), and weight elevated (17% vs. 6%).
  • In pediatric sufferers lower than 2 years outdated (infants), the incidence of neurologic toxicities was not considerably completely different than for the opposite age teams, however its manifestations have been completely different; the one occasion phrases reported have been agitation, headache, insomnia, somnolence, and irritability. Infants additionally had an elevated incidence of hypokalemia (50%) in comparison with different pediatric age cohorts (15-20%) or adults (17%).

Dosage and Administration Pointers

  • BLINCYTO® is run as a steady intravenous infusion at a relentless move fee utilizing an infusion pump which ought to be programmable, lockable, non-elastomeric, and have an alarm.
  • It is rather essential that the directions for preparation (together with admixing) and administration offered within the full Prescribing Data are strictly adopted to attenuate treatment errors (together with underdose and overdose).

Please see full Prescribing Data and medicine information for BLINCYTO at www.BLINCYTO.com.

About BeiGene

BeiGene is a worldwide, commercial-stage biotechnology firm centered on discovering, growing, manufacturing, and commercializing progressive medicines to enhance remedy outcomes and entry for sufferers worldwide. Our 4,700+ workers in China, america, Australia, Europe, and elsewhere are dedicated to expediting the event of a various pipeline of novel therapeutics. We presently market two internally found oncology merchandise: BTK inhibitor BRUKINSA® (zanubrutinib) in america and China, and anti-PD-1 antibody tislelizumab in China. We additionally market or plan to market in China further oncology merchandise licensed from Amgen Inc., Celgene Logistics Sàrl, a Bristol Myers Squibb (BMS) firm, and EUSA Pharma. To be taught extra about BeiGene, please go to www.beigene.com and comply with us on Twitter at @BeiGeneUSA.

Ahead-Wanting Statements

This press launch accommodates forward-looking statements inside the which means of the Personal Securities Litigation Reform Act of 1995 and different federal securities legal guidelines, together with statements concerning the commercialization and potential advantages of BLINCYTO®; and BeiGene’s plans and expectations for the commercialization of its and Amgen’s different oncology merchandise and pipeline belongings. Precise outcomes may differ materially from these indicated within the forward-looking statements because of varied essential components, together with BeiGene’s capacity to display the efficacy and security of its drug candidates; the scientific outcomes for its drug candidates, which may not assist additional growth or advertising and marketing approval; actions of regulatory companies, which may have an effect on the initiation, timing and progress of scientific trials and advertising and marketing approval; BeiGene’s capacity to realize business success for its marketed merchandise and drug candidates, if accepted; BeiGene’s capacity to acquire and preserve safety of mental property for its expertise and medicines; BeiGene’s reliance on third events to conduct drug growth, manufacturing and different companies; BeiGene’s restricted working historical past and BeiGene’s capacity to acquire further funding for operations and to finish the event and commercialization of its drug candidates; the affect of the COVID-19 pandemic on the Firm’s scientific growth, business and different operations, in addition to these dangers extra absolutely mentioned within the part entitled “Risk Factors” in BeiGene’s most up-to-date quarterly report on Kind 10-Q, in addition to discussions of potential dangers, uncertainties, and different essential components in BeiGene’s subsequent filings with the U.S. Securities and Change Fee. All info on this press launch is as of the date of this press launch, and BeiGene undertakes no obligation to replace such info until required by legislation.

BLINCYTO® and BiTE® are registered logos of Amgen Inc.


1 Mayo Clinic. Acute lymphocytic leukemia. https://www.mayoclinic.org/diseases-conditions/acute-lymphocytic-leukemia/symptoms-causes/syc-20369077

2 Baljevic M, Jabbour E, O’Brien S, Kantarjian HM (2016). “Acute Lymphoblastic Leukemia”.

3 World Most cancers Observatory. https://gco.iarc.fr/in the present day/information/factsheets/populations/160-china-fact-sheets.pdf

4 Leukaemia Care. Relapse in Acute Lymphoblastic Leukaemia (ALL). https://media.leukaemiacare.org.uk/wp-content/uploads/Relapse-in-Acute-Lymphoblastic-Leukaemia-ALL-Internet-Model.pdf

Judie Simms

Judie Simms

Contact: [email protected]

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