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        • Today Bitcoin Price at $6,800 USD
        • Pandemic Is Changing BTC Usage in ‘Unexpected Ways’
        • Macropay on Alternative & local payment methods that are reshaping global e-commerce
        • Bank of America is preparing for a flood of Applications to Small-Business Loan
        • Microsoft might be the best tech stock in this market
        • US Airlines To Work Collectively, Consolidate Flights
        • Bank of America maintaining business continuity and protecting the bottom line
        • US long-term mortgage rates drop
        • Bitcoin Price Bulls have been rejected at $7,000
        • Stock Market: 4 Top Stock Trades for Wednesday: NVDA, AVGO, BAC, IQ
        • Stock Market April 2 – Edge Higher; Oil Surges, Bonds Fall, Dollar Rose
        • Chase bank will raise up to $10 billion
          • Bitcoin Price Simply Surged to $6,500 After Over 10% Weekend Crash
          • Today Bitcoin Price at $7,000: BTC Leaps to Retest $7,000
          • Bank of America agreed to allow 50,000 mortgage customers to defer payments
        • Bitcoin Price Prediction April: Three Key Causes Why BTC May Plunge Beneath $5,000
          • Roll up the Sleeves! American Airlines was down -10.34%
          • Mortgage calculator rates today April 2, 2020
          • Mortgage Calculator Small businesses: SB have ‘a million inquiries’ regarding check help loans
          • Bitcoin Price Today April 1 – Bitcoin Takes Tumble
            • With Bank of America card you can request a payment deferral online
              • Bank of America fields 150,000 installment deferral demands
            • Coronavirus – Travel Insurance no cover cancellations
              • Bank of America said it won’t cut any positions
          • Bitcoin Price Today April 2 – BTC rise to $6,700
          • Mortgage calculator rates today March 31, 2020
          • Bitcoin Price Momentum Sign Reverses, Bull Run Lastly Inbound?
          • Bitcoin Price Recovering After a Sharp Decline
          • Fintech News Airbnb – How hosts are fighting back against Covid-19 fallout
          • Market Stock Boeing – Challenging Times Ahead for Boeing Stock
        • Bank of America U.S. Minimum Hourly Wage Reaches $20
          • Bitcoin Price Bulls – is Forming a Bull Cross After Rallying to $6,500
          • P2P Crowdlending – Average Interest Rate 18%
          • $633 Million BTC Transferred For Simply $0.26 Payment
        • Prime ICO Advertising and marketing Companies
        • Bank of America will provide up to $250 million
        • Bank of America VC: You tend to do the wrong thing at the wrong time
          • Bitcoin Price Jump as Coronavirus Curve Begins to Flatten
            • Bitcoin Price Today April 3
            • Bitcoin Price Is Sometimes Bullish in Q2
            • Bitcoin Price Tumble Beneath $ 6,000
            • BTC Price Today 5 | April, 2020
            • Bitcoin Price and S&P 500 – Here’s how much bitcoin beat the Dow and S&P 500 in the first quarter
              • Today Bitcoin Price at $6,600
                • Bitcoin Price Bulls Reaches: “Live or Die”
                • BTC Price Today | 6 April 2020
          • Bank of America sees big year for Microsoft ahead
            • American Airlines coronavirus downgrade
              • Bitcoin Price Rejected $6,600
              • Bitcoin Price Trace It Will Fall to $ 5 K
              • BTC Price Today April 4
                • Stock Market Today 31 March, 2020
              • US Bank Raises $586M Against COVID-19
                • Bank of America’s Solid Liquidity to Help Covid-19 Crisis
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      • Mortgage Calculator – Students Benefits
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      • Mortgage Calculator Modification – What Is?
      • Mortgage Calculator Canada: Rates Are Rising
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        • Mortgage rates today, April 3, 2020 plus reviews
          • cmc currency details
            • cmc exchange details
              • Shortcodes
        • Microsoft Vulnerability: Hundreds of Microsoft Servers Contaminated By Crypto-Mining Botnet Since 2018
          • Cision PR Newswire
          • Coupons – Best websites
            • Aeromexico Rewards Chart
            • Get Avios Points Free
        • Today Bitcoin Price at $6,800 USD
        • Pandemic Is Changing BTC Usage in ‘Unexpected Ways’
        • Macropay on Alternative & local payment methods that are reshaping global e-commerce
        • Bank of America is preparing for a flood of Applications to Small-Business Loan
        • Microsoft might be the best tech stock in this market
        • US Airlines To Work Collectively, Consolidate Flights
        • Bank of America maintaining business continuity and protecting the bottom line
        • US long-term mortgage rates drop
        • Bitcoin Price Bulls have been rejected at $7,000
        • Stock Market: 4 Top Stock Trades for Wednesday: NVDA, AVGO, BAC, IQ
        • Stock Market April 2 – Edge Higher; Oil Surges, Bonds Fall, Dollar Rose
        • Chase bank will raise up to $10 billion
          • Bitcoin Price Simply Surged to $6,500 After Over 10% Weekend Crash
          • Today Bitcoin Price at $7,000: BTC Leaps to Retest $7,000
          • Bank of America agreed to allow 50,000 mortgage customers to defer payments
        • Bitcoin Price Prediction April: Three Key Causes Why BTC May Plunge Beneath $5,000
          • Roll up the Sleeves! American Airlines was down -10.34%
          • Mortgage calculator rates today April 2, 2020
          • Mortgage Calculator Small businesses: SB have ‘a million inquiries’ regarding check help loans
          • Bitcoin Price Today April 1 – Bitcoin Takes Tumble
            • With Bank of America card you can request a payment deferral online
              • Bank of America fields 150,000 installment deferral demands
            • Coronavirus – Travel Insurance no cover cancellations
              • Bank of America said it won’t cut any positions
          • Bitcoin Price Today April 2 – BTC rise to $6,700
          • Mortgage calculator rates today March 31, 2020
          • Bitcoin Price Momentum Sign Reverses, Bull Run Lastly Inbound?
          • Bitcoin Price Recovering After a Sharp Decline
          • Fintech News Airbnb – How hosts are fighting back against Covid-19 fallout
          • Market Stock Boeing – Challenging Times Ahead for Boeing Stock
        • Bank of America U.S. Minimum Hourly Wage Reaches $20
          • Bitcoin Price Bulls – is Forming a Bull Cross After Rallying to $6,500
          • P2P Crowdlending – Average Interest Rate 18%
          • $633 Million BTC Transferred For Simply $0.26 Payment
        • Prime ICO Advertising and marketing Companies
        • Bank of America will provide up to $250 million
        • Bank of America VC: You tend to do the wrong thing at the wrong time
          • Bitcoin Price Jump as Coronavirus Curve Begins to Flatten
            • Bitcoin Price Today April 3
            • Bitcoin Price Is Sometimes Bullish in Q2
            • Bitcoin Price Tumble Beneath $ 6,000
            • BTC Price Today 5 | April, 2020
            • Bitcoin Price and S&P 500 – Here’s how much bitcoin beat the Dow and S&P 500 in the first quarter
              • Today Bitcoin Price at $6,600
                • Bitcoin Price Bulls Reaches: “Live or Die”
                • BTC Price Today | 6 April 2020
          • Bank of America sees big year for Microsoft ahead
            • American Airlines coronavirus downgrade
              • Bitcoin Price Rejected $6,600
              • Bitcoin Price Trace It Will Fall to $ 5 K
              • BTC Price Today April 4
                • Stock Market Today 31 March, 2020
              • US Bank Raises $586M Against COVID-19
                • Bank of America’s Solid Liquidity to Help Covid-19 Crisis
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      • Best Online Savings Accounts of February 2020
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      • 6% cd rates – They Exists ?
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      • Best Credit Cards for Students 2020
      • Best Airline Credit Card 2020
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      • Best Rewards Credit Card 2020
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      • 11 Best Prepaid Debit Cards of 2020
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      • Lowe’s Credit Card
      • Get Revolut Card + £50
      • Qantas Credit Card
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      • How many credit cards should I have?
      • Is Discover Visa or Mastercard?
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      • Wells Fargo Propel – Review
      • Walmart Money Card – Review
      • Credit One Credit Card Review
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      • Travel credit card reviews 2020
      • Petal Credit Card Review
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      • Best Mortgage for Low Down Payment 2020
      • Best Mortgage Rates
      • Best VA Mortgage Lenders of 2020
      • Greatest On-line Mortgage Lenders
      • The Best Mortgage Lenders for First Time Home Buyers
    • Mortgage Calculators
      • Mortgage calculator rates today April 1, 2020
      • Mortgage Calculator – Students Benefits
      • Mortgage Calculator – Homeowners and renters Get Payment Relief
      • Calculator for mortgage to millennials
      • Mortgage Calculator Modification – What Is?
      • Mortgage Calculator Canada: Rates Are Rising
      • Mortgage Calculator Home – Is it time to repair your own home mortgage?
      • Mortgage Calculator
      • Mortgage Calculator Rates Today April 3
      • Mortgage Calculator Online
      • Mortgage Calculator Coronavirus: UK mortgage market goes into lockdown
    • Mortgage Guides
      • Lending
      • How Mortgage Forbearance Works Under CARES Act
      • Stimulus Check
    • Mortgage Companies
      • Nationstar Mortgage
      • Roundpoint Mortgage
      • Midland Mortgage
      • Simple Mortgage Calculator
      • Freedom Mortgage
      • SunTrust Mortgage
  • Commodities
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      • WTI Oil Prices
      • Brent Crude
      • Crude Oil
    • Agricultural Products
      • Corns
    • Livestock & Meat
      • Lean Hogs
    • Precious Metals
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      • Gold
        • Best Place to Buy Gold
        • Price of Gold
        • 5 Ways In order to Buy Gold
        • Gold Price Chart
        • Gold Futures
      • Silver
    • Industrial Metals
      • Copper
  • Insurtech
    • Insurtech “Best of…”
      • Best Life Insurance of 2020
      • The Best Renters Insurance Companies 2020
      • Best Pet Insurance Providers of 2020
      • Best Home Insurance Companies for 2020
      • Best Car Insurance Quotes Online
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Amgen – Rep. Katie Porter’s new report: Pharma mergers hinder cancer research and drug development

Judie Simms by Judie Simms
January 29, 2021
in Amgen
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Home » Amgen – Rep. Katie Porter’s new report: Pharma mergers hinder cancer research and drug development

Amgen – Rep. Katie Porter’s new report: Pharma mergers hinder cancer research and drug development

Success in the pharmaceutical industry these days often looks something like this. A small, scrappy biotech research company comes up with a promising new treatment. Then a major pharmaceutical manufacturer will acquire that smaller company, along with its intellectual property, and bring the treatment to market.

The big pharma company makes money on the retail sales. The smaller outfit makes money when it’s acquired by Big Pharma. Everybody wins … right?

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Not necessarily, according to a new investigation from Rep. Katie Porter (D-CA) shared exclusively with Vox. Porter’s office zeroed in on Immunex, a small biotech firm that was bought by one of the major pharma companies in the early 2000s — and promptly saw its culture of innovation and risk-taking start to deteriorate.

These transactions happen all the time. The number of mergers and acquisitions by the top 25 pharma firms doubled from 2006 to 2016. In 2018, small companies accounted for 64 percent of the new drugs brought to market that year, up from 31 percent in 2009. There was a business logic to this shift, according to a 2014 paper from the University of Pennsylvania: The large drug companies felt their own R&D pipelines weren’t producing enough results to justify the cost. So they switched to acquiring small companies and helping those therapies get FDA approval and mass market distribution.

In an ideal world, this system could make sense. The big drug company deploys its know-how to help an innovative product reach patients. But too often, Porter contends citing the findings of her investigation, these mergers and acquisitions end up squelching innovation. Her report cites prior research that found R&D and new patents declined after a company was acquired.

“The less competition that exists in the pharmaceutical industry,” Porter writes, “the less likely the industry will actually focus on innovation and new cures that can save lives.”

How the Amgen-Immnex merger helped set back cancer research

Amgen acquired Immunex in 2002. The bigger company had been eager to get its hands on a new treatment for rheumatoid arthritis being developed by the smaller biotech firm. The treatment, called Enbrel, was projected to bring in billions of dollars in annual sales.

This kind of acquisition happens all the time, according to research cited in Porter’s report. Increasingly, the business model of large drug makers is to use their immense resources to buy up other companies that have already done the legwork on developing a therapy, rather than spending their own money on research and development.

According to her report, which included interviews with several former employees, a former Immunex scientist reached out to her office after hearing testimony from an Amgen executive that he thought downplayed the role of Immunex in developing Enbrel.

This scientist, Laurent Galibert, and several other former Immunex (and, eventually, Amgen) employees described what happened at the company after Amgen acquired it: Amgen ended most of Immunex’s research into immunotherapy for cancer treatment. This was in the early 2000s, when immunotherapy (which tries to activate the body’s immune system to fight a cancer) was still on the fringes of mainstream science.

Today, immunotherapies are seen as one of the most promising frontiers in cancer treatment. Immunex was years ahead of the game — only to see those efforts stall out once it was gobbled up by a bigger fish, according to its former employees.

“We had anticipated immunotherapy when everyone else thought it was a dream,” Galbraight told Porter’s office. “It took everyone else 11 years to realize that we were right.”

What can be done about all of this?

Porter has some prescriptions for situations like this. She wants the Federal Trade Commission to review prior mergers and to reevaluate its standards for the anti-competitive risks of any future mergers. She is also pressing Congress to pass legislation that would bring small mergers, currently exempt from FTC oversight, under the agency’s purview.

Consolidation in health care is a problem much bigger than the pharma industry. Hospitals have been merging with one another and buying up physician practices; health insurers have been consolidating as well. The overwhelming consensus of researchers is that this market consolidation leads to higher prices and lower quality for US patients.

US health care relies on markets. Almost all health care providers, both doctors and hospitals, are private. More than half of health care is privately financed. The feds and state governments play an important role in setting the rules of the road, and in paying for much of the medical care Americans receive, but the country’s health system depends on healthy competition to deliver care to people and to restrain costs.

According to Martin Gaynor at Carnegie Mellon, who authored a paper last year on how health care markets could be made more efficient, the average hospital market in the US is considered “highly concentrated” according to the criteria used by federal agencies. So is the average market for specialist physicians and health insurers. Primary care doctors just barely miss the cut, but it’s close.

“Something I would be concerned about is so many geographic areas in the US are dominated by one really big health system. They don’t want more competition,” Gaynor says. “If you’re a firm and you’ve merged or acquired to dominate the market, you want to maintain that position, enhance it if you can.”

The conditions are ripe for anti-competitive contracting in many places, and we know that higher prices, which providers can negotiate under these circumstances, account for most of the health care spending growth seen over the last decade.

Health care has a lot of issues, and antitrust enforcement can be part of the solution

Antitrust enforcement is usually slow (it took nearly 10 years for the Sutter case to be resolved) and it’s by nature surgical (every individual monopoly gets targeted with its own enforcement case). A more aggressive federal government can make examples out of bad actors, but in order to get costs under control across the country, more sweeping reforms are probably needed.

But big changes to US health care are hard. Single payer is off the table for the time being. Even rate-setting, like the kind seen in Maryland, may too aggressive for the more moderate members of the Democratic Senate majority, especially because the health care industry is sure to mobilize against such a proposal.

Nobody is talking about shiny new health care cost controls in the middle of a pandemic when health care workers have been hammered. Porter’s ambitions could also be hampered by pharma’s new political clout after delivering Covid-19 vaccines in record time.

But medical consolidation isn’t going away. It is a structural problem driving the nation’s health care affordability crisis. If Biden is serious about doing something, he’ll need to contend with the problems described in this new report.

This story appears in VoxCare, a newsletter from Vox on the latest twists and turns in America’s health care debate. Sign up to get VoxCare in your inbox along with more health care stats and news.



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